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AAP Issues Updated Guidance on Palivizumab Use for the 2022-2023 RSV Season



The American Academy of Pediatrics (AAP) has printed up to date steerage on using palivizumab prophylaxis to stop hospitalization from extreme respiratory syncytial virus (RSV) an infection through the 2022-2023 RSV season.

RSV exercise sometimes begins within the late fall and extends by spring, with peak exercise occurring in early February. As of mid-November 2022, there was a surge of RSV exercise in all areas in the USA with a major variety of hospitalizations and sicknesses.

Within the up to date RSV steerage, the AAP continues to help using palivizumab in eligible infants. Palivizumab is a monoclonal antibody presently marketed below the commerce identify Synagis for the prevention of significant decrease respiratory tract illness attributable to RSV in pediatric sufferers. Synagis is run intramuscularly as soon as month-to-month all through the RSV season. 


Proceed Studying

For areas with persistently excessive ranges of RSV illness exercise within the fall and winter, the AAP helps offering greater than 5 consecutive doses of palivizumab in eligible kids. Based mostly on just a few printed research, there isn’t any proof of elevated frequency or severity of adversarial occasions with the extra doses, in response to the AAP.

The steerage states that “Given this info, along with the recognized efficacy of palivizumab and unpredictable epidemiology of RSV for the reason that summer season of 2021, the AAP recommends programmatic consideration of offering greater than 5 consecutive doses of palivizumab relying on the period of the present RSV surge in a given area of the nation.”

The AAP will proceed to observe RSV exercise by knowledge offered by the Nationwide Respiratory and Enteric Virus Surveillance System.

References

  1. American Academy of Pediatrics provides steerage on RSV prophylaxis, dealing with surge of pediatric sufferers with respiratory infections. Information launch. American Academy of Pediatrics. Accessed November 18, 2022. https://www.aap.org/en/news-room/news-releases/aap/2022/american-academy-of-pediatrics-offers-guidance-on-rsv-prophylaxis-handling-surge-of-pediatric-patients-with-respiratory-infections/.
  2. Up to date steerage: use of palivizumab prophylaxis to stop hospitalization from extreme respiratory syncytial virus an infection through the 2022-2023 RSV season. Information launch. American Academy of Pediatrics. Accessed November 18, 2022. https://www.aap.org/en/pages/2019-novel-coronavirus-covid-19-infections/clinical-guidance/interim-guidance-for-use-of-palivizumab-prophylaxis-to-prevent-hospitalization/.

This text initially appeared on MPR




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